Satisfactory screening for cystic fibrosis with the BM meconium procedure.
نویسندگان
چکیده
The Boehringer Mannheim test (BM test) for cystic fibrosis has been applied to 15 734 neonates. A positive result occurred in 130, seven of whom were subsequently shown to have the disease. To our knowledge no cases have been missed. Tests have been performed centrally by experienced laboratory staff and the false-positive rate of 0.83% is considered acceptable. It is important to follow up weak as well as strongly positive reactions to the BM test strip.
منابع مشابه
Plasma proteins in meconium from normal infants and from babies with cystic fibrosis.
Meconium from babies with cystic fibrosis (CF) has been shown by Green and Shwachman (1968) to contain readily detectable amounts of albumin. Screening for the disease is therefore possible by testing meconium specimens for the presence of albumin with albustix or Boehringer test tape. Any screening procedure, however, requires the availability of reliable methods for checking positive and doub...
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Prosser, R., Owen, H., Bull, F., Parry, B., Smerkinich, J., Goodwin, H. A., and Dathan, J. (1974). Archives of Disease in Childhood, 49, 597. Screening for cystic fibrosis by examination ofmeconium. The value of detecting albumin in meconium as a screening procedure for cystic fibrosis (CF) has been assessed on 34,228 samples in South Wales and North Staffordshire over a 4-year period; simultan...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 34 8 شماره
صفحات -
تاریخ انتشار 1981